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Inhibition of RANK signaling as a potential immunotherapy in breast cancer
RANK signaling in mouse mammary tumor cells exerts an immunosuppressive environment by promoting the infiltration of pro-tumorigenic neutrophils and preventing CD8 T cell recruitment. Single-agent denosumab led to an increased tumor immune infiltration by lymphocytes and CD8 + T cells in breast canc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128215/ https://www.ncbi.nlm.nih.gov/pubmed/34026334 http://dx.doi.org/10.1080/2162402X.2021.1923156 |