Neutrophil stimulation with citrullinated histone H4 slows down calcium influx and reduces NET formation compared with native histone H4

Peptidylarginine deiminase 4 (PAD4) catalyzes posttranslational modification of many target proteins through converting protein arginine or mono-methylarginine to citrulline. Neutrophil extracellular trap (NET) formation is the most dramatic manifestation of PAD4-mediated hypercitrullination reactio...

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Detalles Bibliográficos
Autores principales: Shi, Lai, Aymonnier, Karen, Wagner, Denisa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128235/
https://www.ncbi.nlm.nih.gov/pubmed/33999963
http://dx.doi.org/10.1371/journal.pone.0251726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128235/
https://www.ncbi.nlm.nih.gov/pubmed/33999963
http://dx.doi.org/10.1371/journal.pone.0251726

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