Generation of the short TRIM32 isoform is regulated by Lys 247 acetylation and a PEST sequence

TRIM32 is an E3 ligase implicated in diverse biological pathways and pathologies such as muscular dystrophy and cancer. TRIM32 are expressed both as full-length proteins, and as a truncated protein. The mechanisms for regulating these isoforms are poorly understood. Here we identify a PEST sequence...

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Detalles Bibliográficos
Autores principales: Garcia-Garcia, Juncal, Overå, Katrine Stange, Khan, Waqas, Sjøttem, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128265/
https://www.ncbi.nlm.nih.gov/pubmed/33999923
http://dx.doi.org/10.1371/journal.pone.0251279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128265/
https://www.ncbi.nlm.nih.gov/pubmed/33999923
http://dx.doi.org/10.1371/journal.pone.0251279

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