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Generation of the short TRIM32 isoform is regulated by Lys 247 acetylation and a PEST sequence
TRIM32 is an E3 ligase implicated in diverse biological pathways and pathologies such as muscular dystrophy and cancer. TRIM32 are expressed both as full-length proteins, and as a truncated protein. The mechanisms for regulating these isoforms are poorly understood. Here we identify a PEST sequence...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128265/ https://www.ncbi.nlm.nih.gov/pubmed/33999923 http://dx.doi.org/10.1371/journal.pone.0251279 |