Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19

Pediatric COVID-19 following SARS-CoV-2 infection is associated with fewer hospitalizations and often milder disease than in adults. A subset of children, however, present with Multisystem Inflammatory Syndrome in Children (MIS-C) that can lead to vascular complications and shock, but rarely death....

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Detalles Bibliográficos
Autores principales: Vella, Laura A., Giles, Josephine R., Baxter, Amy E., Oldridge, Derek A., Diorio, Caroline, Kuri-Cervantes, Leticia, Alanio, Cécile, Pampena, M. Betina, Wu, Jennifer E., Chen, Zeyu, Huang, Yinghui Jane, Anderson, Elizabeth M., Gouma, Sigrid, McNerney, Kevin O., Chase, Julie, Burudpakdee, Chakkapong, Lee, Jessica H., Apostolidis, Sokratis A., Huang, Alexander C., Mathew, Divij, Kuthuru, Oliva, Goodwin, Eileen C., Weirick, Madison E., Bolton, Marcus J., Arevalo, Claudia P., Ramos, Andre, Jasen, CJ, Conrey, Peyton E, Sayed, Samir, Giannini, Heather M., D’Andrea, Kurt, Meyer, Nuala J., Behrens, Edward M., Bassiri, Hamid, Hensley, Scott E., Henrickson, Sarah E., Teachey, David T., Betts, Michael R., Wherry, E. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128303/
https://www.ncbi.nlm.nih.gov/pubmed/33653907
http://dx.doi.org/10.1126/sciimmunol.abf7570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128303/
https://www.ncbi.nlm.nih.gov/pubmed/33653907
http://dx.doi.org/10.1126/sciimmunol.abf7570

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