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PTBP1 Targets ILK to Regulate the Hypoxia-Induced Phenotypic Transformation of Pulmonary Artery Smooth Muscle Cells

PURPOSE: Pulmonary hypertension (PH) is a pathological process mainly characterized by the progressive increase in pulmonary vascular resistance. The degradation of pulmonary artery smooth muscle cells (PASMCs) from contractile/differentiated phenotype to synthetic/dedifferentiated phenotype is a ke...

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Detalles Bibliográficos
Autores principales: Yan, Gaoliang, Sun, Renhua, Chen, Zhongpu, Pan, Xiaodong, Sheng, Zulong, Tang, Chengchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128346/
https://www.ncbi.nlm.nih.gov/pubmed/34012255
http://dx.doi.org/10.2147/DDDT.S275000