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Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition

Head and neck squamous cell carcinoma (HNSCC), one of the most common malignancies worldwide, often has a poor prognosis due to the associated metastasis and chemoresistance. Hence, the development of more effective chemotherapeutics is critical. Neferine, a bisbenzylisoquinoline alkaloid isolated f...

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Detalles Bibliográficos
Autores principales: Zhu, Fengshuo, Li, Xiaoguang, Tang, Xiao, Jiang, Junjian, Han, Yu, Li, Yinuo, Ma, Chunyue, Liu, Zhonglong, He, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128420/
https://www.ncbi.nlm.nih.gov/pubmed/33982791
http://dx.doi.org/10.3892/ijmm.2021.4957