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Neferine promotes the apoptosis of HNSCC through the accumulation of p62/SQSTM1 caused by autophagic flux inhibition
Head and neck squamous cell carcinoma (HNSCC), one of the most common malignancies worldwide, often has a poor prognosis due to the associated metastasis and chemoresistance. Hence, the development of more effective chemotherapeutics is critical. Neferine, a bisbenzylisoquinoline alkaloid isolated f...
Autores principales: | Zhu, Fengshuo, Li, Xiaoguang, Tang, Xiao, Jiang, Junjian, Han, Yu, Li, Yinuo, Ma, Chunyue, Liu, Zhonglong, He, Yue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128420/ https://www.ncbi.nlm.nih.gov/pubmed/33982791 http://dx.doi.org/10.3892/ijmm.2021.4957 |
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