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Transcriptome-wide association analysis of brain structures yields insights into pleiotropy with complex neuropsychiatric traits

Structural variations of the human brain are heritable and highly polygenic traits, with hundreds of associated genes identified in recent genome-wide association studies (GWAS). Transcriptome-wide association studies (TWAS) can both prioritize these GWAS findings and also identify additional gene-t...

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Detalles Bibliográficos
Autores principales: Zhao, Bingxin, Shan, Yue, Yang, Yue, Yu, Zhaolong, Li, Tengfei, Wang, Xifeng, Luo, Tianyou, Zhu, Ziliang, Sullivan, Patrick, Zhao, Hongyu, Li, Yun, Zhu, Hongtu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128893/
https://www.ncbi.nlm.nih.gov/pubmed/34001886
http://dx.doi.org/10.1038/s41467-021-23130-y