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Transcriptome-wide association analysis of brain structures yields insights into pleiotropy with complex neuropsychiatric traits
Structural variations of the human brain are heritable and highly polygenic traits, with hundreds of associated genes identified in recent genome-wide association studies (GWAS). Transcriptome-wide association studies (TWAS) can both prioritize these GWAS findings and also identify additional gene-t...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128893/ https://www.ncbi.nlm.nih.gov/pubmed/34001886 http://dx.doi.org/10.1038/s41467-021-23130-y |