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Running the full human developmental clock in interspecies chimeras using alternative human stem cells with expanded embryonic potential

Human pluripotent stem cells (hPSCs) can generate specialized cell lineages that have great potential for regenerative therapies and disease modeling. However, the developmental stage of the lineages generated from conventional hPSC cultures in vitro are embryonic in phenotype, and may not possess t...

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Detalles Bibliográficos
Autores principales: Thomas, Justin, Zimmerlin, Ludovic, Huo, Jeffrey S., Considine, Michael, Cope, Leslie, Zambidis, Elias T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128894/
https://www.ncbi.nlm.nih.gov/pubmed/34001907
http://dx.doi.org/10.1038/s41536-021-00135-1