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Running the full human developmental clock in interspecies chimeras using alternative human stem cells with expanded embryonic potential
Human pluripotent stem cells (hPSCs) can generate specialized cell lineages that have great potential for regenerative therapies and disease modeling. However, the developmental stage of the lineages generated from conventional hPSC cultures in vitro are embryonic in phenotype, and may not possess t...
Autores principales: | Thomas, Justin, Zimmerlin, Ludovic, Huo, Jeffrey S., Considine, Michael, Cope, Leslie, Zambidis, Elias T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128894/ https://www.ncbi.nlm.nih.gov/pubmed/34001907 http://dx.doi.org/10.1038/s41536-021-00135-1 |
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