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TRPM7 kinase-mediated immunomodulation in macrophage plays a central role in magnesium ion-induced bone regeneration

Despite the widespread observations on the osteogenic effects of magnesium ion (Mg(2+)), the diverse roles of Mg(2+) during bone healing have not been systematically dissected. Here, we reveal a previously unknown, biphasic mode of action of Mg(2+) in bone repair. During the early inflammation phase...

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Detalles Bibliográficos
Autores principales: Qiao, Wei, Wong, Karen H. M., Shen, Jie, Wang, Wenhao, Wu, Jun, Li, Jinhua, Lin, Zhengjie, Chen, Zetao, Matinlinna, Jukka P., Zheng, Yufeng, Wu, Shuilin, Liu, Xuanyong, Lai, Keng Po, Chen, Zhuofan, Lam, Yun Wah, Cheung, Kenneth M. C., Yeung, Kelvin W. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128914/
https://www.ncbi.nlm.nih.gov/pubmed/34001887
http://dx.doi.org/10.1038/s41467-021-23005-2