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Visualization of Kinase Inhibition-Related Adverse Events Using the Japanese Adverse Drug Event Report Database

INTRODUCTION: Small molecule tyrosine kinase inhibitors (TKIs) inhibit not only the target kinase but also various kinases as off-target inhibitors not mentioned in the package insert. However, there are no reports that comprehensively examine the relationship between adverse events and kinase affin...

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Detalles Bibliográficos
Autores principales: Mizuno, Takahito, Sakai, Takamasa, Tanabe, Kouichi, Umemura, Takumi, Goto, Nobuyuki, Ohtsu, Fumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128962/
https://www.ncbi.nlm.nih.gov/pubmed/33686612
http://dx.doi.org/10.1007/s40801-021-00235-w