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FOXC2 Autoregulates Its Expression in the Pulmonary Endothelium After Endotoxin Stimulation in a Histone Acetylation-Dependent Manner

The innate immune response of pulmonary endothelial cells (EC) to lipopolysaccharide (LPS) induces Forkhead box protein C2 (FOXC2) activation through Toll Like Receptor 4 (TLR4). The mechanisms by which FOXC2 expression is regulated in lung EC under LPS stimulation remain unclear. We postulated that...

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Detalles Bibliográficos
Autores principales: Xia, Sheng, Yu, Wei, Menden, Heather, Younger, Scott T., Sampath, Venkatesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129010/
https://www.ncbi.nlm.nih.gov/pubmed/34017833
http://dx.doi.org/10.3389/fcell.2021.657662