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In silico Exploration of Interactions Between Potential COVID-19 Antiviral Treatments and the Pore of the hERG Potassium Channel—A Drug Antitarget

Background: In the absence of SARS-CoV-2 specific antiviral treatments, various repurposed pharmaceutical approaches are under investigation for the treatment of COVID-19. Antiviral drugs considered for this condition include atazanavir, remdesivir, lopinavir-ritonavir, and favipiravir. Whilst the c...

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Detalles Bibliográficos
Autores principales: Al-Moubarak, Ehab, Sharifi, Mohsen, Hancox, Jules C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129016/
https://www.ncbi.nlm.nih.gov/pubmed/34017865
http://dx.doi.org/10.3389/fcvm.2021.645172