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Nucleosome plasticity is a critical element of chromatin liquid–liquid phase separation and multivalent nucleosome interactions

Liquid–liquid phase separation (LLPS) is an important mechanism that helps explain the membraneless compartmentalization of the nucleus. Because chromatin compaction and LLPS are collective phenomena, linking their modulation to the physicochemical features of nucleosomes is challenging. Here, we de...

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Detalles Bibliográficos
Autores principales: Farr, Stephen E., Woods, Esmae J., Joseph, Jerelle A., Garaizar, Adiran, Collepardo-Guevara, Rosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129070/
https://www.ncbi.nlm.nih.gov/pubmed/34001913
http://dx.doi.org/10.1038/s41467-021-23090-3