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DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization

The decrease of neurotransmitter dopamine (DA) levels in the intestine is closely related to the development of inflammatory bowel disease (IBD). However, the functional relevance and underlying mechanistic basis of the effects of DA signaling on IBD remains unclear. Here, we observed that the DRD5...

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Detalles Bibliográficos
Autores principales: Liu, Lu, Wu, Yuqing, Wang, Bingwei, Jiang, Yuying, Lin, Lin, Li, Xiaoxi, Yang, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129081/
https://www.ncbi.nlm.nih.gov/pubmed/34001860
http://dx.doi.org/10.1038/s41419-021-03778-6