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DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization
The decrease of neurotransmitter dopamine (DA) levels in the intestine is closely related to the development of inflammatory bowel disease (IBD). However, the functional relevance and underlying mechanistic basis of the effects of DA signaling on IBD remains unclear. Here, we observed that the DRD5...
Autores principales: | Liu, Lu, Wu, Yuqing, Wang, Bingwei, Jiang, Yuying, Lin, Lin, Li, Xiaoxi, Yang, Shuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129081/ https://www.ncbi.nlm.nih.gov/pubmed/34001860 http://dx.doi.org/10.1038/s41419-021-03778-6 |
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