Proline codon pair selection determines ribosome pausing strength and translation efficiency in bacteria

The speed of mRNA translation depends in part on the amino acid to be incorporated into the nascent chain. Peptide bond formation is especially slow with proline and two adjacent prolines can even cause ribosome stalling. While previous studies focused on how the amino acid context of a Pro-Pro moti...

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Detalles Bibliográficos
Autores principales: Krafczyk, Ralph, Qi, Fei, Sieber, Alina, Mehler, Judith, Jung, Kirsten, Frishman, Dmitrij, Lassak, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129111/
https://www.ncbi.nlm.nih.gov/pubmed/34002016
http://dx.doi.org/10.1038/s42003-021-02115-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129111/
https://www.ncbi.nlm.nih.gov/pubmed/34002016
http://dx.doi.org/10.1038/s42003-021-02115-z

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