Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets

Cryopreservation offers the potential to increase the availability of pancreatic islets for treatment of diabetic patients. However, current protocols, which use dimethyl sulfoxide (DMSO), lead to poor cryosurvival of islets. We demonstrate that equilibration of mouse islets with small molecules in...

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Detalles Bibliográficos
Autores principales: Dolezalova, Nikola, Gruszczyk, Anja, Barkan, Kerry, Gamble, John A., Galvin, Sam, Moreth, Till, O’Holleran, Kevin, Mahbubani, Krishnaa T., Higgins, Jackie A., Gribble, Fiona M., Reimann, Frank, Surmacki, Jakub, Andrews, Simon, Casey, John J., Pampaloni, Francesco, Murphy, Michael P., Ladds, Graham, Slater, Nigel K. H., Saeb-Parsy, Kourosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129116/
https://www.ncbi.nlm.nih.gov/pubmed/34001961
http://dx.doi.org/10.1038/s41598-021-89853-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129116/
https://www.ncbi.nlm.nih.gov/pubmed/34001961
http://dx.doi.org/10.1038/s41598-021-89853-6

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