Cisplatin and phenanthriplatin modulate long-noncoding RNA expression in A549 and IMR90 cells revealing regulation of microRNAs, Wnt/β-catenin and TGF-β signaling

The monofunctional platinum(II) complex, phenanthriplatin, acts by blocking transcription, but its regulatory effects on long-noncoding RNAs (lncRNAs) have not been elucidated relative to traditional platinum-based chemotherapeutics, e.g., cisplatin. Here, we treated A549 non-small cell lung cancer...

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Detalles Bibliográficos
Autores principales: Monroe, Jerry D., Moolani, Satya A., Irihamye, Elvin N., Lett, Katheryn E., Hebert, Michael D., Gibert, Yann, Smith, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129125/
https://www.ncbi.nlm.nih.gov/pubmed/34001990
http://dx.doi.org/10.1038/s41598-021-89911-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129125/
https://www.ncbi.nlm.nih.gov/pubmed/34001990
http://dx.doi.org/10.1038/s41598-021-89911-z

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