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12-Hydroxyeicosapentaenoic acid inhibits foam cell formation and ameliorates high-fat diet-induced pathology of atherosclerosis in mice

Atherosclerosis is a chronic inflammatory disease associated with macrophage aggregate and transformation into foam cells. In this study, we sought to investigate the impact of dietary intake of ω3 fatty acid on the development of atherosclerosis, and demonstrate the mechanism of action by identifyi...

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Detalles Bibliográficos
Autores principales: Nagatake, Takahiro, Shibata, Yuki, Morimoto, Sakiko, Node, Eri, Sawane, Kento, Hirata, So-ichiro, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Saika, Azusa, Hosomi, Koji, Tomonaga, Takeshi, Kunisawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129127/
https://www.ncbi.nlm.nih.gov/pubmed/34001916
http://dx.doi.org/10.1038/s41598-021-89707-1