Cargando…

12-Hydroxyeicosapentaenoic acid inhibits foam cell formation and ameliorates high-fat diet-induced pathology of atherosclerosis in mice

Atherosclerosis is a chronic inflammatory disease associated with macrophage aggregate and transformation into foam cells. In this study, we sought to investigate the impact of dietary intake of ω3 fatty acid on the development of atherosclerosis, and demonstrate the mechanism of action by identifyi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nagatake, Takahiro, Shibata, Yuki, Morimoto, Sakiko, Node, Eri, Sawane, Kento, Hirata, So-ichiro, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Saika, Azusa, Hosomi, Koji, Tomonaga, Takeshi, Kunisawa, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129127/ https://www.ncbi.nlm.nih.gov/pubmed/34001916 http://dx.doi.org/10.1038/s41598-021-89707-1

Ejemplares similares

Dietary Omega-3 Fatty Acid Dampens Allergic Rhinitis via Eosinophilic Production of the Anti-Allergic Lipid Mediator 15-Hydroxyeicosapentaenoic Acid in Mice
por: Sawane, Kento, et al.
Publicado: (2019)

Vitamin B1 Supports the Differentiation of T Cells through TGF-β Superfamily Production in Thymic Stromal Cells
por: Hirata, So-ichiro, et al.
Publicado: (2020)

Induction of unique macrophage subset by simultaneous stimulation with LPS and IL-4
por: Ishida, Kei, et al.
Publicado: (2023)

Mead acid inhibits retinol-induced irritant contact dermatitis via peroxisome proliferator-activated receptor alpha
por: Saika, Azusa, et al.
Publicado: (2023)

Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques
por: Nagatake, Takahiro, et al.
Publicado: (2022)

17(S),18(R)‐epoxyeicosatetraenoic acid generated by cytochrome P450 BM‐3 from Bacillus megaterium inhibits the development of contact hypersensitivity via G‐protein‐coupled receptor 40‐mediated neutrophil suppression
por: Saika, Azusa, et al.
Publicado: (2019)

Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL‐expressing plasmacytoid dendritic cells in mice
por: Hirata, So‐ichiro, et al.
Publicado: (2020)

Host- and Microbe-Dependent Dietary Lipid Metabolism in the Control of Allergy, Inflammation, and Immunity
por: Saika, Azusa, et al.
Publicado: (2019)

Metabolism of Dietary and Microbial Vitamin B Family in the Regulation of Host Immunity
por: Yoshii, Ken, et al.
Publicado: (2019)

Selective expression of claudin-5 in thymic endothelial cells regulates the blood–thymus barrier and T-cell export
por: Nagatake, Takahiro, et al.
Publicado: (2020)

The Synthesis of 3-(R)- and 3-(S)-Hydroxyeicosapentaenoic Acid
por: Gjessing, Gard, et al.
Publicado: (2022)

Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota
por: Hosomi, Koji, et al.
Publicado: (2022)

Chemically Synthesized Alcaligenes Lipid A as an Adjuvant to Augment Immune Responses to Haemophilus Influenzae Type B Conjugate Vaccine
por: Liu, Zilai, et al.
Publicado: (2021)

8-Hydroxyeicosapentaenoic Acid Reduces Adipogenesis and Inflammation in 3T3-L1 Adipocytes
por: Zu, Yujiao, et al.
Publicado: (2022)

Comprehensive proteomic profiling of plasma and serum phosphatidylserine-positive extracellular vesicles reveals tissue-specific proteins
por: Muraoka, Satoshi, et al.
Publicado: (2022)

Automated Proteomics Sample Preparation of Phosphatidylserine-Positive Extracellular Vesicles from Human Body Fluids
por: Muraoka, Satoshi, et al.
Publicado: (2022)

Immunological association of inducible bronchus-associated lymphoid tissue organogenesis in Ag85B-rHPIV2 vaccine-induced anti-tuberculosis mucosal immune responses in mice
por: Nagatake, Takahiro, et al.
Publicado: (2018)

Emerging roles of metabolites of ω3 and ω6 essential fatty acids in the control of intestinal inflammation
por: Nagatake, Takahiro, et al.
Publicado: (2019)

Impaired mucociliary motility enhances antigen-specific nasal IgA immune responses to a cholera toxin-based nasal vaccine
por: Lan, Huangwenxian, et al.
Publicado: (2020)

Lentinula Edodes Mycelia extract regulates the function of antigen-presenting cells to activate immune cells and prevent tumor-induced deterioration of immune function
por: Kajiyama, Shota, et al.
Publicado: (2023)

Improved phosphoproteomic analysis for phosphosignaling and active-kinome profiling in Matrigel-embedded spheroids and patient-derived organoids
por: Abe, Yuichi, et al.
Publicado: (2018)

Deep Phospho- and Phosphotyrosine Proteomics Identified Active Kinases and Phosphorylation Networks in Colorectal Cancer Cell Lines Resistant to Cetuximab
por: Abe, Yuichi, et al.
Publicado: (2017)

Identification of Human Gut Microbiome Associated with Enterolignan Production
por: Sawane, Kento, et al.
Publicado: (2022)

Lymphoid Tissue–Resident Alcaligenes Establish an Intracellular Symbiotic Environment by Creating a Unique Energy Shift in Dendritic Cells
por: Hosomi, Koji, et al.
Publicado: (2020)

Persistent colonization of non-lymphoid tissue-resident macrophages by Stenotrophomonas maltophilia
por: Takahashi, Ichiro, et al.
Publicado: (2019)

Lipopolysaccharide Derived From the Lymphoid-Resident Commensal Bacteria Alcaligenes faecalis Functions as an Effective Nasal Adjuvant to Augment IgA Antibody and Th17 Cell Responses
por: Wang, Yunru, et al.
Publicado: (2021)

TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity
por: Ogura, Hayato, et al.
Publicado: (2017)

Method for preparing DNA from feces in guanidine thiocyanate solution affects 16S rRNA-based profiling of human microbiota diversity
por: Hosomi, Koji, et al.
Publicado: (2017)

Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine
por: Wang, Yunru, et al.
Publicado: (2020)

The Specific Roles of Vitamins in the Regulation of Immunosurveillance and Maintenance of Immunologic Homeostasis in the Gut
por: Hosomi, Koji, et al.
Publicado: (2017)

Diversity of energy metabolism in immune responses regulated by micro-organisms and dietary nutrition
por: Hosomi, Koji, et al.
Publicado: (2020)

Chemically Synthesized Alcaligenes Lipid A Shows a Potent and Safe Nasal Vaccine Adjuvant Activity for the Induction of Streptococcus pneumoniae-Specific IgA and Th17 Mediated Protective Immunity
por: Yoshii, Ken, et al.
Publicado: (2020)

Comprehensive characterization of the phosphoproteome of gastric cancer from endoscopic biopsy specimens
por: Abe, Yuichi, et al.
Publicado: (2020)

Temporal dynamics from phosphoproteomics using endoscopic biopsy specimens provides new therapeutic targets in stage IV gastric cancer
por: Hirano, Hidekazu, et al.
Publicado: (2022)

8-Hydroxyeicosapentaenoic Acid Decreases Plasma and Hepatic Triglycerides via Activation of Peroxisome Proliferator-Activated Receptor Alpha in High-Fat Diet-Induced Obese Mice
por: Yamada, Hidetoshi, et al.
Publicado: (2016)

Fatty acid metabolism in the host and commensal bacteria for the control of intestinal immune responses and diseases
por: Hosomi, Koji, et al.
Publicado: (2019)

Systematic identification of ALK substrates by integrated phosphoproteome and interactome analysis
por: Adachi, Jun, et al.
Publicado: (2022)

Dietary iodine attenuates allergic rhinitis by inducing ferroptosis in activated B cells
por: Nakamura, Yutaka, et al.
Publicado: (2023)

Lanatoside C Promotes Foam Cell Formation and Atherosclerosis
por: Shi, Huairui, et al.
Publicado: (2016)

Macrophage Foam Cell-Targeting Immunization Attenuates Atherosclerosis
por: Wang, Fazhan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7nmmnk2oe6ni8t1luiu78bn5aq