Intranasal immunization with inactivated chlamydial elementary bodies formulated in VCG-chitosan nanoparticles induces robust immunity against intranasal Chlamydia psittaci challenge

Vaccines based on live attenuated Chlamydia elementary bodies (EBs) can cause disease in vaccinated animals and the comparably safer inactivated whole EBs are only marginally protective. Recent studies show that a vaccine formulation comprising UV-inactivated EBs (EB) and appropriate mucosal deliver...

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Detalles Bibliográficos
Autores principales: Zuo, Zonghui, Zou, Yongjuan, Li, Qiang, Guo, Yongxia, Zhang, Tianyuan, Wu, Jie, He, Cheng, Eko, Francis O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129140/
https://www.ncbi.nlm.nih.gov/pubmed/34001988
http://dx.doi.org/10.1038/s41598-021-89940-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129140/
https://www.ncbi.nlm.nih.gov/pubmed/34001988
http://dx.doi.org/10.1038/s41598-021-89940-8

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