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The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac

The brush border is comprised of microvilli surface protrusions on the apical surface of epithelia. This specialized structure greatly increases absorptive surface area and plays crucial roles in human health. However, transcriptional regulatory networks controlling brush border genes are not fully...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Luo, Shirley, Dupre, Abigail, Vasoya, Roshan P., Parthasarathy, Aditya, Aita, Rohit, Malhotra, Raj, Hur, Joseph, Toke, Natalie H., Chiles, Eric, Yang, Min, Cao, Weihuan, Flores, Juan, Ellison, Christopher E., Gao, Nan, Sahota, Amrik, Su, Xiaoyang, Bonder, Edward M., Verzi, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129143/
https://www.ncbi.nlm.nih.gov/pubmed/34001900
http://dx.doi.org/10.1038/s41467-021-22761-5