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The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac
The brush border is comprised of microvilli surface protrusions on the apical surface of epithelia. This specialized structure greatly increases absorptive surface area and plays crucial roles in human health. However, transcriptional regulatory networks controlling brush border genes are not fully...
Autores principales: | Chen, Lei, Luo, Shirley, Dupre, Abigail, Vasoya, Roshan P., Parthasarathy, Aditya, Aita, Rohit, Malhotra, Raj, Hur, Joseph, Toke, Natalie H., Chiles, Eric, Yang, Min, Cao, Weihuan, Flores, Juan, Ellison, Christopher E., Gao, Nan, Sahota, Amrik, Su, Xiaoyang, Bonder, Edward M., Verzi, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129143/ https://www.ncbi.nlm.nih.gov/pubmed/34001900 http://dx.doi.org/10.1038/s41467-021-22761-5 |
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