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Examination of BDNF Treatment on BACE1 Activity and Acute Exercise on Brain BDNF Signaling

Perturbations in metabolism results in the accumulation of beta-amyloid peptides, which is a pathological feature of Alzheimer’s disease. Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) is the rate limiting enzyme responsible for beta-amyloid production. Obesogenic diets increase BACE1...

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Detalles Bibliográficos
Autores principales: Baranowski, Bradley J., Hayward, Grant C., Marko, Daniel M., MacPherson, Rebecca E. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129185/
https://www.ncbi.nlm.nih.gov/pubmed/34017238
http://dx.doi.org/10.3389/fncel.2021.665867