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Epigenetic Regulation of Genomic Stability by Vitamin C

DNA methylation plays an important role in the maintenance of genomic stability. Ten-eleven translocation proteins (TETs) are a family of iron (Fe(2+)) and α-KG -dependent dioxygenases that regulate DNA methylation levels by oxidizing 5-methylcystosine (5mC) to generate 5-hydroxymethylcytosine (5hmC...

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Detalles Bibliográficos
Autores principales: Brabson, John P., Leesang, Tiffany, Mohammad, Sofia, Cimmino, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129186/
https://www.ncbi.nlm.nih.gov/pubmed/34017357
http://dx.doi.org/10.3389/fgene.2021.675780