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Epigenetic Regulation of Genomic Stability by Vitamin C
DNA methylation plays an important role in the maintenance of genomic stability. Ten-eleven translocation proteins (TETs) are a family of iron (Fe(2+)) and α-KG -dependent dioxygenases that regulate DNA methylation levels by oxidizing 5-methylcystosine (5mC) to generate 5-hydroxymethylcytosine (5hmC...
Autores principales: | Brabson, John P., Leesang, Tiffany, Mohammad, Sofia, Cimmino, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129186/ https://www.ncbi.nlm.nih.gov/pubmed/34017357 http://dx.doi.org/10.3389/fgene.2021.675780 |
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