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A Comparative Analysis of the Lipoprotein(a) and Low-Density Lipoprotein Proteomic Profiles Combining Mass Spectrometry and Mendelian Randomization

BACKGROUND: Lipoprotein(a) (Lp[a]), which consists of a low-density lipoprotein (LDL) bound to apolipoprotein(a), is one of the strongest genetic risk factors for atherosclerotic cardiovascular diseases. Few studies have performed hypothesis-free direct comparisons of the Lp(a) and the LDL proteomes...

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Detalles Bibliográficos
Autores principales: Bourgeois, Raphaëlle, Girard, Arnaud, Perrot, Nicolas, Guertin, Jakie, Mitchell, Patricia L., Couture, Christian, Gotti, Clarisse, Bourassa, Sylvie, Poggio, Paolo, Mass, Elvira, Capoulade, Romain, Scipione, Corey A., Després, Audrey-Anne, Couture, Patrick, Droit, Arnaud, Pibarot, Philippe, Boffa, Michael B., Thériault, Sébastien, Koschinsky, Marlys L., Mathieu, Patrick, Arsenault, Benoit J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129481/
https://www.ncbi.nlm.nih.gov/pubmed/34027348
http://dx.doi.org/10.1016/j.cjco.2020.11.019