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Natural Killer Cells Generated From Human Induced Pluripotent Stem Cells Mature to CD56(bright)CD16(+)NKp80(+/-) In-Vitro and Express KIR2DL2/DL3 and KIR3DL1

The differentiation of human induced pluripotent stem cells (hiPSCs) into T and natural killer (NK) lymphocytes opens novel possibilities for developmental studies of immune cells and in-vitro generation of cell therapy products. In particular, iPSC-derived NK cells gained interest in adoptive anti-...

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Detalles Bibliográficos
Autores principales: Euchner, Johanna, Sprissler, Jasmin, Cathomen, Toni, Fürst, Daniel, Schrezenmeier, Hubert, Debatin, Klaus-Michael, Schwarz, Klaus, Felgentreff, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129508/
https://www.ncbi.nlm.nih.gov/pubmed/34017328
http://dx.doi.org/10.3389/fimmu.2021.640672