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MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer

Colorectal cancer is one of the most common malignancies worldwide. Oxaliplatin is the first-line chemotherapeutic agent for the treatment of advanced colorectal cancer. However, acquired resistance to oxaliplatin limits its therapeutic efficacy, and the underlying mechanism remains largely unclear....

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Detalles Bibliográficos
Autores principales: Qian, Xiao-Lan, Zhou, Fang, Xu, Song, Jiang, Jian, Chen, Zhi-Peng, Wang, Shao-Kai, Zuo, Yun, Ni, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129568/
https://www.ncbi.nlm.nih.gov/pubmed/34017681
http://dx.doi.org/10.3389/fonc.2021.638537