Antibodies Elicited by the Shigella sonnei GMMA Vaccine in Adults Trigger Complement-Mediated Serum Bactericidal Activity: Results From a Phase 1 Dose Escalation Trial Followed by a Booster Extension

Shigella is the second most deadly diarrheal disease among children under five years of age, after rotavirus, with high morbidity and mortality in developing countries. Currently, no vaccine is widely available, and the increasing levels of multidrug resistance make Shigella a high priority for vacc...

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Detalles Bibliográficos
Autores principales: Micoli, Francesca, Rossi, Omar, Conti, Valentino, Launay, Odile, Sciré, Antonella Silvia, Aruta, Maria Grazia, Nakakana, Usman Nasir, Marchetti, Elisa, Rappuoli, Rino, Saul, Allan, Martin, Laura B., Necchi, Francesca, Podda, Audino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129577/
https://www.ncbi.nlm.nih.gov/pubmed/34017343
http://dx.doi.org/10.3389/fimmu.2021.671325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129577/
https://www.ncbi.nlm.nih.gov/pubmed/34017343
http://dx.doi.org/10.3389/fimmu.2021.671325

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