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Role of ex vivo Expanded Mesenchymal Stromal Cells in Determining Hematopoietic Stem Cell Transplantation Outcome

Overall, the human organism requires the production of ∼1 trillion new blood cells per day. Such goal is achieved via hematopoiesis occurring within the bone marrow (BM) under the tight regulation of hematopoietic stem and progenitor cell (HSPC) homeostasis made by the BM microenvironment. The BM ni...

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Detalles Bibliográficos
Autores principales: Crippa, Stefania, Santi, Ludovica, Berti, Margherita, De Ponti, Giada, Bernardo, Maria Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129582/
https://www.ncbi.nlm.nih.gov/pubmed/34017834
http://dx.doi.org/10.3389/fcell.2021.663316