Integrative chemogenomic analysis identifies small molecules that partially rescue ΔF508‐CFTR for cystic fibrosis

Rare diseases affect 10% of the first‐world population, yet over 95% lack even a single pharmaceutical treatment. In the present age of information, we need ways to leverage our vast data and knowledge to streamline therapeutic development and lessen this gap. Here, we develop and implement an innov...

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Detalles Bibliográficos
Autores principales: Hodos, Rachel A., Strub, Matthew D., Ramachandran, Shyam, Meleshkevitch, Ella A., Boudko, Dmitri Y., Bridges, Robert J., Dudley, Joel T., McCray, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129714/
https://www.ncbi.nlm.nih.gov/pubmed/33934548
http://dx.doi.org/10.1002/psp4.12626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129714/
https://www.ncbi.nlm.nih.gov/pubmed/33934548
http://dx.doi.org/10.1002/psp4.12626

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