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Alzheimer mutant speeds APP transport
APP(S198P) segregates with rare familial forms of Alzheimer’s disease and resides within exon 5, unlike 27 other mutations that reside in exons 16 or 17. In this issue, Zhang et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20210313) show that the brains of APP(S198P) transgenic mice accumulat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129791/ https://www.ncbi.nlm.nih.gov/pubmed/33988687 http://dx.doi.org/10.1084/jem.20210511 |