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Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate autophagy

Dynamic targeting of the ULK1 complex to the ER is crucial for initiating autophagosome formation and for subsequent formation of ER–isolation membrane (IM; autophagosomal precursor) contact during IM expansion. Little is known about how the ULK1 complex, which comprises FIP200, ULK1, ATG13, and ATG...

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Detalles Bibliográficos
Autores principales: Liu, Nan, Zhao, Hongyu, Zhao, Yan G., Hu, Junjie, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129792/
https://www.ncbi.nlm.nih.gov/pubmed/33988678
http://dx.doi.org/10.1083/jcb.202012091