Selective MAP1LC3C (LC3C) autophagy requires noncanonical regulators and the C-terminal peptide

LC3s are canonical proteins necessary for the formation of autophagosomes. We have previously established that two paralogs, LC3B and LC3C, have opposite activities in renal cancer, with LC3B playing an oncogenic role and LC3C a tumor-suppressing role. LC3C is an evolutionary late gene present only...

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Detalles Bibliográficos
Autores principales: Bischoff, Megan E., Zang, Yuanwei, Chu, Johnson, Price, Adam D., Ehmer, Birgit, Talbot, Nicholas J., Newbold, Michael J., Paul, Anurag, Guan, Jun-Lin, Plas, David R., Meller, Jarek, Czyzyk-Krzeska, Maria F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129795/
https://www.ncbi.nlm.nih.gov/pubmed/33988680
http://dx.doi.org/10.1083/jcb.202004182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129795/
https://www.ncbi.nlm.nih.gov/pubmed/33988680
http://dx.doi.org/10.1083/jcb.202004182

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