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Cell membrane permeability and defective G2/M block as factors potentially contributing to increased cell chemosensitivity. SeAx cell line as an example
BACKGROUND: Immortalized mammalian cell lines are a valuable research tool, though they represent a highly simplified model. Due to accumulated mutations they may not reflect characteristics of the disease or even the tissue they derive from. OBJECTIVE: We aim to pinpoint factors distinguishing SeAx...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129889/ https://www.ncbi.nlm.nih.gov/pubmed/34027132 http://dx.doi.org/10.1016/j.bbrep.2021.101005 |