LPS decreases CFTR open probability and mucociliary transport through generation of reactive oxygen species

Lipopolysaccharide (LPS) serves as the interface between gram-negative bacteria (GNB) and the innate immune response in respiratory epithelial cells (REC). Herein, we describe a novel biological role of LPS that permits GNB to persist in the respiratory tract through inducing CFTR and mucociliary dy...

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Detalles Bibliográficos
Autores principales: Cho, Do Yeon, Zhang, Shaoyan, Lazrak, Ahmed, Skinner, Daniel, Thompson, Harrison M., Grayson, Jessica, Guroji, Purushotham, Aggarwal, Saurabh, Bebok, Zsuzsanna, Rowe, Steven M., Matalon, Sadis, Sorscher, Eric J., Woodworth, Bradford A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129928/
https://www.ncbi.nlm.nih.gov/pubmed/33971543
http://dx.doi.org/10.1016/j.redox.2021.101998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129928/
https://www.ncbi.nlm.nih.gov/pubmed/33971543
http://dx.doi.org/10.1016/j.redox.2021.101998

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