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MDM2 induces EMT via the B-Raf signaling pathway through 14-3-3

MDM2 proto-oncogene, E3 ubiquitin protein ligase (MDM2) is a well-known oncogene and has been reported to be closely associated with epithelial-to-mesenchymal transition (EMT). The present study first demonstrated that the expression levels of MDM2 were markedly increased in TGF-β-induced EMT using...

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Detalles Bibliográficos
Autores principales: Ou, Mengting, Xu, Xichao, Chen, Ying, Li, Li, Zhang, Lu, Liao, Yi, Sun, Weichao, Quach, Christine, Feng, Jianguo, Tang, Liling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8129971/
https://www.ncbi.nlm.nih.gov/pubmed/33955525
http://dx.doi.org/10.3892/or.2021.8071