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Cochlea cell-specific marker expression upon in vitro Hes1 knockdown

NOTCH pathway proteins, including the transcriptional factor HES1, play crucial roles in the development of the inner ear by means of the lateral inhibition mechanism, in which supporting cells have their phenotype preserved while they are prevented from becoming hair cells. Genetic manipulation of...

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Detalles Bibliográficos
Autores principales: Batissoco, A.C., Lezirovitz, K., Zanatta, D.B., Hemza, C.R.M.L., Vasques, L.R., Strauss, B.E., Mingroni-Netto, R.C., Haddad, L.A., Bento, R.F., Oiticica, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130059/
https://www.ncbi.nlm.nih.gov/pubmed/34008754
http://dx.doi.org/10.1590/1414-431X2020e10579