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Cochlea cell-specific marker expression upon in vitro Hes1 knockdown
NOTCH pathway proteins, including the transcriptional factor HES1, play crucial roles in the development of the inner ear by means of the lateral inhibition mechanism, in which supporting cells have their phenotype preserved while they are prevented from becoming hair cells. Genetic manipulation of...
Autores principales: | Batissoco, A.C., Lezirovitz, K., Zanatta, D.B., Hemza, C.R.M.L., Vasques, L.R., Strauss, B.E., Mingroni-Netto, R.C., Haddad, L.A., Bento, R.F., Oiticica, J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130059/ https://www.ncbi.nlm.nih.gov/pubmed/34008754 http://dx.doi.org/10.1590/1414-431X2020e10579 |
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