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Leveraging epigenetics to enhance the efficacy of immunotherapy
BACKGROUND: Epigenetic mechanisms regulate chromatin accessibility patterns that govern interaction of transcription machinery with genes and their cis-regulatory elements. Mutations that affect epigenetic mechanisms are common in cancer. Because epigenetic modifications are reversible many anticanc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130138/ https://www.ncbi.nlm.nih.gov/pubmed/34001289 http://dx.doi.org/10.1186/s13148-021-01100-x |