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Leveraging epigenetics to enhance the efficacy of immunotherapy

BACKGROUND: Epigenetic mechanisms regulate chromatin accessibility patterns that govern interaction of transcription machinery with genes and their cis-regulatory elements. Mutations that affect epigenetic mechanisms are common in cancer. Because epigenetic modifications are reversible many anticanc...

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Detalles Bibliográficos
Autores principales:	Licht, Jonathan D., Bennett, Richard L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130138/ https://www.ncbi.nlm.nih.gov/pubmed/34001289 http://dx.doi.org/10.1186/s13148-021-01100-x

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