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Increased PARylation impacts the DNA methylation process in type 2 diabetes mellitus

BACKGROUND: Epigenetic modifications, such as DNA methylation, can influence the genetic susceptibility to type 2 diabetes mellitus (T2DM) and the progression of the disease. Our previous studies demonstrated that the regulation of the DNA methylation pattern involves the poly(ADP-ribosyl)ation (PAR...

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Detalles Bibliográficos
Autores principales: Zampieri, Michele, Bacalini, Maria Giulia, Barchetta, Ilaria, Scalea, Stefania, Cimini, Flavia Agata, Bertoccini, Laura, Tagliatesta, Stefano, De Matteis, Giovanna, Zardo, Giuseppe, Cavallo, Maria Gisella, Reale, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130175/
https://www.ncbi.nlm.nih.gov/pubmed/34001206
http://dx.doi.org/10.1186/s13148-021-01099-1