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Converging Evidence on D-Amino Acid Oxidase–Dependent Enhancement of Hippocampal Firing Activity and Passive Avoidance Learning in Rats

BACKGROUND: N-methyl-D-aspartate (NMDA) receptor activation requires the binding of a co-agonist on the glycine-binding site. D-serine is the main endogenous co-agonist of NMDA receptors, and its availability significantly depends on the activity of the metabolic enzyme D-amino acid oxidase (DAAO)....

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Detalles Bibliográficos
Autores principales: Nagy, Lili Veronika, Bali, Zsolt Kristóf, Kapus, Gábor, Pelsőczi, Péter, Farkas, Bence, Lendvai, Balázs, Lévay, György, Hernádi, István
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130201/
https://www.ncbi.nlm.nih.gov/pubmed/33305805
http://dx.doi.org/10.1093/ijnp/pyaa095