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Worenine reverses the Warburg effect and inhibits colon cancer cell growth by negatively regulating HIF-1α

BACKGROUND: Some natural compounds inhibit cancer cell growth in various cancer cell lines with fewer side effects than traditional chemotherapy. Here, we explore the pharmacological effects and mechanisms of worenine (isolated from Coptis chinensis) against colorectal cancer. METHODS: The effects o...

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Detalles Bibliográficos
Autores principales: Ji, Lijiang, Shen, Weixing, Zhang, Feng, Qian, Jie, Jiang, Jie, Weng, Liping, Tan, Jiani, Li, Liu, Chen, Yugen, Cheng, Haibo, Sun, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130299/
https://www.ncbi.nlm.nih.gov/pubmed/34006215
http://dx.doi.org/10.1186/s11658-021-00263-y