Cargando…

Rethinking pioglitazone as a cardioprotective agent: a new perspective on an overlooked drug

Since 1985, the thiazolidinedione pioglitazone has been widely used as an insulin sensitizer drug for type 2 diabetes mellitus (T2DM). Although fluid retention was early recognized as a safety concern, data from clinical trials have not provided conclusive evidence for a benefit or a harm on cardiac...

Descripción completa

Detalles Bibliográficos
Autores principales: Nesti, Lorenzo, Tricò, Domenico, Mengozzi, Alessandro, Natali, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130304/
https://www.ncbi.nlm.nih.gov/pubmed/34006325
http://dx.doi.org/10.1186/s12933-021-01294-7