Surface-modified engineered exosomes attenuated cerebral ischemia/reperfusion injury by targeting the delivery of quercetin towards impaired neurons

BACKGROUND: The incidence of ischemic stroke in the context of vascular disease is high, and the expression of growth-associated protein-43 (GAP43) increases when neurons are damaged or stimulated, especially in a rat model of middle cerebral artery occlusion/reperfusion (MCAO/R). EXPERIMENTAL: DESI...

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Detalles Bibliográficos
Autores principales: Guo, Lin, Huang, Zhixuan, Huang, Lijuan, Liang, Jia, Wang, Peng, Zhao, Liang, Shi, Yijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130330/
https://www.ncbi.nlm.nih.gov/pubmed/34001136
http://dx.doi.org/10.1186/s12951-021-00879-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8130330/
https://www.ncbi.nlm.nih.gov/pubmed/34001136
http://dx.doi.org/10.1186/s12951-021-00879-4

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